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Assimilate the concept of "Rational Drug Therapy".
Practice "Rational Use of Drugs
Develop good prescribing skills
Understand the essence of "Essential Drug Concept" and be competent to make/modify the essential drug list.
Imbibe "Medical Ethics" and uphold the principles in patient care, drug development and research.
To train students in activities related to detection, assessment, understanding and preventing adverse drug reactions (Pharmacovigilance).
Emphasis on drug interactions when two or more drugs are given together

Head of Departments message

Department of Pharmacology strives to train undergraduate students of the college with the following mission statement

To impart the understanding of the pharmacological basis of therapeutics so as to enable the future doctors to prescribe rationally, to differentiate hype on drugs from truth and work actively to contribute to the achievement of the national health goals'

The faculty undertake and participate in research projects in addition to their teaching work. The department also inculcates & encourages research aptitude in undergraduate students and helps them to undertake short term research projects under the aegis of Indian Council of Medical Research. Hands on practical training of drug assays and pharmacometrics are supported by thoughtfully planned seminars and journal article presentations.

Facilities in Department

The department has all the facilities for undergraduate teaching as per the regulations of the Medical Council of India. The teaching programme is being carried out efficiently on a regular basis with the help of lectures, practicals, seminars, demonstrations and integrated teaching classes. Projects are submitted by small groups of students based on various clinical problems collected from the hospital. This makes the students aware of rational drug use, over-prescription, under-prescription, drug interactions and adverse drug reactions.

A) Pharmacovigilance Centre

The department runs a pharmacovigilance centre which is actively involved in the detection, assessment, understanding and prevention of the Adverse Drug Events (ADE) in the hospital. The centre guided by its hospital committee conducts periodic review of the adverse drug events, initiates education programmes and has taken the lead in formulating ADE management protocols.

B) Other Dept. Activities

Other activities of the department include integrated teaching programmes, continuing medical / nursing education programmes, formulation of drug related management protocols and taking classes for other departments.Academic

C) Pharmacy Lab

A pharmacy lab in the department is equipped with all the essential instruments and reagents for demonstration and practice of pharmacy exercises.

D) Experimental Pharmacology Lab

This well-equipped lab provides facility for demonstration of animal experiments and charts

E) Demonstration Room

With a capacity to seat approximately 30 students, this mini-hall in the department is well-equipped with audio-visual aids including OHP & LCD projectors, black board and audio system

F)Museum

The department Museum contains sample drugs, pharmacokinetic and pharmacodynamic charts, photographs of medicinal plants, plant products, models of receptors and exhibits depicting history of medicine to aid illustrative teaching.

G) Clinical Pharmacology Research Room

A dedicated room with essential computer support is available for clinical pharmacology research.

F)Research Room

The research room contains all equipment’s as specified by Medical Council of India.

F)Library

The department library has 80 books on medical and nursing pharmacology and allied specialities for faculty reference.

Subject curriculum

COURSE CONTENT

Total duration of Para-clinical teaching - 3 Semesters (III, IV, V)

Total number of teaching hours allotted to Pharmacology 300 hours

Learning methods-Lectures, tutorials, Practical

A) INTRODUCTION TO PHARMACOLOGY – A Foundation to Clinical Practice

B) GENERAL PHARMACOLOGY:

Pharmacokinetics, Pharmacodynamics, Application to Pharmacotherapeutics: Relevance of Pharmacokinetics and dynamics in clinical practice, Sequelae of repeated administration of drugs & Adverse Drug Reactions

C) AUTONOMIC PHARMACOLOGY:

General Considerations, Adrenergic agonists & antagonists

Cholinergic agonists, Anticholinesterases, Antimuscarinic drugs, Skeletal muscle relaxants

D) CARDIOVASCULAR SYSEM:

General Considerations and Overview of antihypertensive therapy;

Diuretics, ACE inhibitors, Sympatholytics & vasodilators,

Antianginal: Nitrates & others ,Calcium channel blockers

Anticoagulants & Coagulants, Thrombolytics & Antiplatelet Agents

Drugs for CCF: Digitalis glycosides & Others

Antiarrhythmic Agents, Agents used for the management of shock, Hypolipidaemic drugs

Role of Nitric oxide and endothelin; Management of CCF, Hypertension, Angina, Shock.

E) HAEMATINICS AND HAEMATOPOIETIC FACTORS

Agents used in therapy of iron deficiency anaemia and megaloblastic anaemia;

Erythropoietin, GM-CSF; Management of anaemia

F) NEUROPSYCHIATRIC PHARMACOLOGY INCLUDING INFLAMMATON, PAIN & SUBSTANCE ABUSE

General Considerations, Sedative-Hypnotics, Psychopharmacology: Antianxiety drugs; Antipsychotics; Antidepressants, Antiepileptics, Anti-Parkinsonian agents; Cerebral vasodilators/nootropics, Local anaesthetics, Analgesics: Opioids; NSAIDs Pharmacotherapy of pain including migraine, rheumatoid arthritis and gout Substance abuse: Management of opioid, alcohol and tobacco addictions

G) MISCELLANEOUS TOPICS - I:

Autocoids, Antiallergics: Antihistaminics, Drugs used for bronchial asthma & cough

Drugs acting on immune system:Immunostimulants, Immunosuppressants;

Pharmacology of vaccines & sera

Drugs acting on the uterus

H) CHEMOTHERAPY INCLUDING CANCER CHEMOTHERAPY:

General considerations,
Antimicrobial agents-Sulphonamides & Cotrimoxazole, Quinoline derivatives, Penicillins,
Aminoglycosides, Macrolides, Tetracyclines & Chloramphenicol
Pharmacotherapy of UTI
General principles of Antimicrobial use
Antimycobacterial therapy, Anti-leprotic agents
Antiprotozoal agents: Antiamoebic, Antimalarials and Anti Kala azar
Pharmacotherapy of TB & Malaria
Antihelminthics, Antifungal agents, Antiviral agents including antiretroviral agents
Pharmacotherapy of STDs,
Principles of cancer chemotherapy and their adverse drug reactions

I) ENDOCRINOLOGY:

Hypothalamic and Anterior Pituitary hormones, Thyroxine and antithyroid agents
Steroids, Oestrogens & antagonists, Progestins & antagonists, Oral contraceptives & profertility agents, Testosterone & anabolic steroids, Agents affecting calcification
Antidiabetic agents: Insulin; Oral antidiabetic drugs, Pharmacotherapy of Diabetes Mellitus

J) AGENTS USED IN GASTROINTESTINAL DISORDERS:

Pharmacotherapy of nausea & vomiting, Pharmacotherapy of peptic ulcer
Management of dyspepsia, diarrhoea and constipation

K) PERIOPERATIVE MANAGEMENT:

Preanaesthetic medication, Preparation of surgical site: antiseptics etc. Local Anaesthetics, Skeletal muscle relaxants Drugs used in post-operative period: analgesics, antiemetics etc.

L) MISCELLANEOUS TOPICS – II

Drug-Drug Interactions Drug use at extremes of age, in pregnancy & in organ dysfunction Use of chelating agents in heavy metal poisonings; Environmental & occupational toxicants and principles of management (particularly cyanide and CO) Ocular pharmacology, Pharmacotherapy of glaucoma & conjunctivitis, Dermatopharmacology

M) RATIONAL PHARMACOTHERAPY:

Prescription writing and P-drug concept, Rational Drug Use; Essential Drug List (EDL) Criticism with reference to Fixed Drug Combinations (FDCs) Use and misuse of commonly used preparations: vitamins, antioxidants, enzymes etc.

Practical’s

I term practical’s

Introduction to Practical Pharmacology, Prescription Writing, Pharmacokinetics I, Routes of Administration: Oral, Routes of Administration: Topical, Routes of Administration: Parenteral, Pharmacokinetics II: Applied Pharmacokinetics

II term practical’s

Pharmacodynamics I (Isolated Tissue, Cat NM junction), Pharmacodynamics II (Dog: BP and Respiration), Screening Techniques for New Drugs, Adverse Drug Reactions, Rational Pharmacotherapy I, Rational Pharmacotherapy II, Sources of Drug Information including scrutiny of Promotional Literature

III term practical’s

Case Study 1, Case Study 2 Revision Practicals

PATTERN OF EXAMINATION

Theory: Marks 80
Paper: I, Marks: 40,Time: 2 Hours
Section A & B: LAQ & SAQ
Paper: II, Marks: 40,Time: 2 Hours
Section A & B: LAQ & SAQ

Practical: Marks 25

Prescription writing
Criticism of a prescription & rewriting
Fixed dose formulation
Clinical Pharmacy (dosage forms, routes of administration, label information and instructions)

Spots

Viva: Marks 15 Internal assessment: Marks 30

List of teaching and non teaching staff

Name	Designation	Qualification	Post PG Experience	email id
Dr. Purnima Raj	Professor & HOD	MD Pharmacology, 2001	14 years	purnima.raj@gmcraigarh.in
Dr. Presenjit Raut	Associate Professor	MD Pharmacology, 2006	10 years	presenjitraut@gmcraigarh.in
Dr. Jharna Sahu	Assistant Professor	MD Pharmacology, 2014	2 years 4 months	jharna.sahu@gmcraigarh.in
Dr. Sumati G Kundu	Assistant Professor	BDS, M.Sc Pharmacology	6 years	sumati.kundu@gmcraigarh.in
Dr.Gulshan Sidar	Demonstrator	MBBS	2 years 2 months	gulshan.sidar@gmcraigarh.in
Dr. Satyam Patel	Demonstrator	MBBS	1 years 2 months	satyam83@patelgmail.com

NON TEACHING STAFF
Mr.Satrohan Kumar – Assistant Grade-3
Mr.Rajkumar Suman- Lab Technician
Miss Jyoti Tiwari- Lab Technician
Miss Himkanti Sidar-Lab attendant
Mrs.Rajkumari Sahu-Peon

DEPARTMENTAL EVENTS

A seminar was presented by Dr. Akash Panda on the topic “Rational use of medicines” on 9.12.2014.      A seminar was presented by Dr. Gulshan Sidar on the topic “Screening of antiepileptic drugs” on 2.1.2015

POSTER/PAPER PRESENTATION

Poster presented by Dr. Purnima Raj, Prof. & Head, in the 3rd International & 6th National Conference of the Indian Society for Rational Pharmacotherapeutics’2014, on “Efficacy & Safety of Misoprostol by sublingual and rectal route in preventing Post Partum Haemorrhage in low risk vaginal delivery”.

PUBLICATIONS

Journals
Dr. Purnima Raj

Raj Purnima, Tembhurnikar P., Agarwal A., Shrivastava PK., Rathore M., Verma VB., “To study awareness of HIV/AIDS in female HIV positive patients and access adverse reactions in female patients on Anti Retro Viral therapy along with their adherence to therapy in Chhattisgarh” 171 – 175, RJPPD, Vol 03, Issue 04, July – August, 2011.

Raj Purnima, Tembhurnikar P., Rathore M., Verma V., Pandey SN., “Antibiotics induced adverse drug reaction monitoring in a teaching hospital of Chhattisgarh.” Research J. Pharmacology and Pharmacodynamics: 4(1): 1012; 13 – 16.

Gedam JK., Jogi S., Vidhyarthi., Raj Purnima. “Misoprostol for second trimester medical abortion: A prospective randomized comparative trial.” Asian Journal of Obstetrics and Gynaecology practice, Vol.3, July –September 2010.

Dr. Presenjit Raut

Evaluation of knowledge, attitude & practice of self medication among II yr B.Sc Nursing students; JDDT, 2014, 4(3), 138-144.

Comparision of analgesic activity of Venlafaxine with Etoricoxib using digital

analgesiometer; RJBPCS; 2014, 5(4), 555-564.

Comparision of analgesic activity of Venlafaxine with Etoricoxib using digital

analgesiometer; RJBPCS; 2014, 5(4), 555-564.

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